Agrochemical Research and Development


Adgyl Life Sciences is a pioneering leader in agrochemical research and development. With a strong commitment to agricultural innovation, we specialize in conducting a wide array of studies that ensure the safety and efficacy of agrochemical products. Our comprehensive portfolio includes genetic toxicology, in vitro assessments, acute studies, repeated dose investigations, developmental and reproductive toxicity, endocrine disruption, neurotoxicity, chronic/carcinogenicity/oncogenicity, metabolism studies, and ecotoxicology.

Genetic Toxicology Studies
  • Bacterial Reverse Mutation Test (Ames Test) (OECD 471)
  • In Vitro Mammalian Chromosomal Aberration Test (CHO cells) (OECD 473)
  • In Vitro Mammalian Chromosomal Aberration Test (Human Peripheral Blood Lymphocytes-HPBL) (OECD 473)
  • In Vitro Mammalian Cell Gene Mutation Test Using the Hprt and xprt genes (OECD 476)
  • In Vitro Mammalian Cell Micronucleus Test (Human Peripheral Blood Lymphocytes-HPBL) (OECD 487)
  • In Vitro Mammalian Cell Gene Mutation Test Using the Thymidine Kinase Gene (OECD 490)
  • Mammalian Erythrocyte Micronucleus Test (OECD 474)
  • Mammalian Bone Marrow Chromosomal Aberration Test (OECD 475)
In Vitro Studies
  • EpiSkin-In Vitro Skin Corrosion (OECD 431)
  • EpiSkin-In Vitro Skin Irritation (OECD 439)
  • In Vitro Eye Irritation [Bovine Corneal Opacity and Permeability (BCOP) Test] (OECD 437)
  • In Vitro Eye Irritation EpiOcular (OECD 492)
  • In Vitro Skin Sensitization [Dermal Peptide Reactivity Assay (DPRA)] (OECD 442C)
  • In Vitro Skin Sensitization- ARE-Nrf2 Luciferase Test Method [KeratinoSens] (OECD 442D)
  • In Vitro Skin Sensitization [Human Cell Line (U937-U-SENS) Activation Test (h-CLAT)] (OECD 442E)
  • In Vitro Skin Absorption: Franz Cell Diffusion Assay (OECD 428)
  • In vitro Cytotoxicity in Balb/c 3T3 LD50 (OECD 129)
Acute Studies
  • Acute Oral Toxicity Study in Rats (OECD 420/423/425)
  • Acute Dermal Toxicity Study in Rats (OECD 402)
  • Acute Inhalation Study in Rats (OECD 403)
  • Acute Dermal Irritation/Corrosion Study in Rabbits (OECD 404)
  • Acute Eye Irritation/Corrosion Study in Rabbits (OECD 405)
  • Skin Sensitization Study in Guinea Pigs (OECD 406)
  • Local Lymph Node Assay (LLNA) in CBA/Ca mice (OECD 429)
Repeated Dose
  • Dose range finding (7 to 14 day) toxicology studies in Mice/Rats
  • Dose range finding (7 to 14 day) toxicology studies in Beagle Dogs*
  • 28-day repeat dose toxicity studies in Mice/Rats
  • 28-day repeat dose toxicity studies in Beagle Dogs*
  • 90-day repeat dose toxicity studies in Mice/Rats
  • 90-day repeat dose toxicity studies in Beagle Dogs*
  • 21/28-day repeat dose dermal toxicity studies in Rats/Rabbits
  • 90-day repeat dose dermal toxicity studies in Rats/Rabbits
  • 28-day Inhalation toxicity studies in Rats
  • 90-day Inhalation toxicity studies in Rats
Developmental and Reproductive Toxicology Studies
  • Prenatal Developmental Toxicity Study in Mice/rats/Rabbits (OECD 414)
  • One Generation Reproductive Toxicity Study in Mice/Rats (OECD 415)
  • Two Generation Reproductive Toxicity Study in Mice/Rats (OECD 416)
  • Reproduction/Developmental Toxicity Screening Test in Rats (OECD 421)
  • Combined Repeated Dose with Reproduction/Developmental Toxicity Screening Test in Rats (OECD 422)
  • Extended One-Generation Reproduction Toxicity Study in Rats (OECD 443)
Endocrine Disruption Studies
  • Uterotrophic Bioassay in Rats (OECD 440)
  • Hershberger Bioassay in Rats (OECD 441)
Neurotoxicity Studies
  • Delayed Neurotoxicity of Organophosphorus substances following acute exposure (OECD 418)
  • Delayed Neurotoxicity of Organophosphorus substances 28-day repeated dose study (OECD 419)
  • Neurotoxicity Study in Rats (OECD 424)
  • Developmental Neurotoxicity Study in Rats (OECD 426)
Chronic / Carcinogenicity / Oncogenicity Studies
  • Carcinogenicity study in Mice/Rats (OECD 451)
  • Chronic Toxicity studies in Mice/Rats (OECD 452)
  • Combined Chronic Toxicity/Carcinogenicity study in Mice/Rats (OECD 453)
Metabolism Studies-Using 14C labeled compounds
  • Toxicokinetics/Mass balance study in rats (OECD 417)
  • Skin absorption study in rats (OECD 427)
  • Metabolism in Livestock -Goat, Chicken and Swine* (OECD 503)
  • Residues in Livestock -Goat, Chicken and Swine* (OECD 505)

*: In-life phase performed at partner facility

Ecotoxicology (Ecotox) studies
  • Acute toxicity test in fish*
  • Acute toxicity test in daphnia*
  • Acute toxicity test in alga*
  • Acute toxicity test in earthworm*
  • Acute toxicity test in honey bee (oral & contact)*
  • Ready biodegradability study (carbon dioxide evolution test)*
  • Acute Oral Toxicity Study in birds [Japanese Quails/Chicken/Pigeon] (OECD 223)
  • Avian Dietary Toxicity Study in Japanese Quails (OECD 205)
  • Reproductive Toxicity in Birds-Japanese Quails (OECD 206)

*: Performed in group company at the same campus

Services Offered Under Agrochemicals

CASE STUDIES