Discovery Chemistry

Medicinal Chemistry:

  • Chemistry do-ability assessment for new biological targets
  • Hit identification and expansion
  • HIT-to-Lead and Lead Optimization

CADD:

  • SBDD and FBDD
  • QSAR, vHTS
  • Physiochemical properties calculation

Synthetic Chemistry:

  • Focused library design and synthesis
  • Scaffolds, building blocks and intermediate synthesis
  • Route optimization and scale-up
  • Natural product analogs
  • Synthesis of reference compound
  • Chiral resolution
  • Carbohydrate chemistry
  • Metabolite identification and synthesis

Analytical Services:

  • Method development and validation
  • Preparative HPLC separation
  • Chiral separation