Annex VII (1 Tonne or More)
- Bacterial Reverse Mutation Test (Ames Test) (OECD 471)
- Acute Oral Toxicity Study in Rats (OECD 420/423/425)
- Acute Dermal Irritation/Corrosion Study in Rabbits (OECD 404)
- Acute Eye Irritation/Corrosion Study in Rabbits (OECD 405)
- Skin Sensitization Study in Guinea Pigs (OECD 406) or
- Local Lymph Node Assay (LLNA) in CBA/Ca mice (OECD 429)
Annex VIII (10 Tonnes or More)
- Bacterial Reverse Mutation Test (Ames Test) (OECD 471)
- In Vitro Mammalian Chromosomal Aberration Test (CHO cells) (OECD 473)
- In Vitro Mammalian Cell Gene Mutation Test Using the Hprt and xprt genes (OECD 476)
- In Vitro Mammalian Cell Micronucleus Test (Human Peripheral Blood Lymphocytes-HPBL) (OECD 487)
- Acute Oral Toxicity Study in Rats (OECD 420/423/425)
- Acute Dermal Toxicity Study in Rats (OECD 402)
- Acute Inhalation Study in Rats (OECD 403)
- Acute Dermal Irritation/Corrosion Study in Rabbits (OECD 404)
- Acute Eye Irritation/Corrosion Study in Rabbits (OECD 405)
- Skin Sensitization Study in Guinea Pigs (OECD 406) or
- Local Lymph Node Assay (LLNA) in CBA/Ca mice (OECD 429)
- 28 Day Repeated Dose (OECD 407)
- Reproductive Toxicity (OECD 421)
- Developmental Toxicity study (OECD 414)
Annex IX (100 Tonnes Or More)
- Bacterial Reverse Mutation Test (Ames Test) (OECD 471)
- In Vitro Mammalian Chromosomal Aberration Test (CHO cells) (OECD 473)
- In Vitro Mammalian Cell Gene Mutation Test Using the Hprt and xprt genes (OECD 476)
- In Vitro Mammalian Cell Micronucleus Test (Human Peripheral Blood Lymphocytes-HPBL) (OECD 487)
- Mammalian Erythrocyte Micronucleus Test (OECD 474)
- Mammalian Bone Marrow Chromosomal Aberration Test (OECD 475)
- Acute Oral Toxicity Study in Rats (OECD 420/423/425)
- Acute Dermal Toxicity Study in Rats (OECD 402)
- Acute Inhalation Study in Rats (OECD 403)
- Acute Dermal Irritation/Corrosion Study in Rabbits (OECD 404)
- Acute Eye Irritation/Corrosion Study in Rabbits (OECD 405)
- Skin Sensitization Study in Guinea Pigs (OECD 406)
- Local Lymph Node Assay (LLNA) in CBA/Ca mice (OECD 429) or
- 90 Day Repeated Dose (OECD 408)
- Reproductive Toxicity (OECD 421)
- Developmental Toxicity Study-Rats (OECD 414)
- Extended One-Generation Reproduction Toxicity Study in Rats (OECD 443)
Annex X (1000 Tonnes or More)
- Bacterial Reverse Mutation Test (Ames Test) (OECD 471)
- In Vitro Mammalian Chromosomal Aberration Test (CHO cells) (OECD 473)
- In Vitro Mammalian Cell Gene Mutation Test Using the Hprt and xprt genes (OECD 476)
- In Vitro Mammalian Cell Micronucleus Test (Human Peripheral Blood Lymphocytes-HPBL) (OECD 487)
- Mammalian Erythrocyte Micronucleus Test (OECD 474)
- Mammalian Bone Marrow Chromosomal Aberration Test (OECD 475)
- Acute Oral Toxicity Study in Rats (OECD 420/423/425)
- Acute Dermal Toxicity Study in Rats (OECD 402)
- Acute Inhalation Study in Rats (OECD 403)
- Acute Dermal Irritation/Corrosion Study in Rabbits (OECD 404)
- Acute Eye Irritation/Corrosion Study in Rabbits (OECD 405)
- Skin Sensitization Study in Guinea Pigs (OECD 406) or
- Local Lymph Node Assay (LLNA) in CBA/Ca mice (OECD 429)
- 90 Day Repeated Dose (OECD 408)
- Reproductive Toxicity (OECD 421)
- Developmental Toxicity Study-Rats & Rabbits (OECD 414)
- Extended One-Generation Reproduction Toxicity Study in Rats (OECD 443)
- Chronic Toxicity (OECD 452)/ Carcinogenicity (Oncogenicity) (OECD 451)
