Cytotoxicity Testing

• Agar diffusion test
• Agar diffusion with extraction test
• MEM elution test
• MTT cytotoxicity test
• Neutral Red Uptake (NRU) test
• Colony formation test

Sensitization Testing

• Guinea Pig Maximization Test (GPMT)
• Buehler Sensitization test
• Local Lymph Node Assay (LLNA)

Irritation Testing

• Intracutaneous reactivity test
• Primary skin irritation test
• Primary ocular irritation test
• Primary buccal (mucosal) irritation test
• Vaginal irritation test
• Rectal irritation test
• Penile irritation test
• Invitro irritation test

Material Mediated Pyrogenicity Testing

Systemic Toxicity Testing

• Acute systemic toxicity Test
• Subacute systemic toxicity testing
  • 28 day (ISO and abridged design) All routes
  • 90 day (ISO and abridged design) All routes
• Chronic systemic toxicity All routes

Implantation Testing in Rat/ Rabbit/ Swine/Sheep/Dog

• Muscle implant for varying periods (1 week to 2 year)
• Subcutaneous implant for varying periods (1 week to 2 year)
• Dental Implants for varying periods (1 week to 2 year)
• Bone implants for varying periods (1 week to 2 year)
• Implantation in organs/tissues for varying periods (1 week to 2 year)

Facilities

• State of the art -surgical suite
• CathLab; ECHO; Doppler
• Vascular image analysis
• Plastic embedding of tissues along with implants
• Scanning Electron Microscopy
• Tissue morphometry software

Device Testing

• Cardiovascular devices
• Orthopedic segment
• Gastrointestinal segment devices 
• Genitourinary segment devices
• Neurological segment devices
• Dental devices
• Other miscellaneous devices

Hemocompatibility Testing

• Hemolysis test (Direct contact and extract method) in Rabbit/human Blood
• Complement Activation Test
• Coagulation Test
• Platelet Activation Test

Genotoxicity Testing

• Bacterial reverse mutation test
• In vitro mammalian chromosomal aberration test in CHO cells
• In vitro mammalian cell gene mutation test using the thymidine kinase gene
• In vitro mammalian chromosomal aberration test in human peripheral blood lymphocytes
• In vitro mammalian cell micronucleus test
• In vivo cytogenetic assay
• In vivo micronucleus test
• In vivo chromosomal aberration 

Carcinogenicity Testing

Ocular Biocompatibility Test with Rabbit Eyes as per ISO 9394

Cytotoxicity Test of Contact Lenses in Combination with Lens Care Solution as per ISO 18189

US Pharmacopeia-National Formulary Testing

• USP <87> In-Vitro Biological Reactivity Cytotoxicity Testing
• USP <88> In-Vivo Biological Reactivity Class IVI Testing