Genetic Toxicology Studies
- Bacterial Reverse Mutation Test (Ames Test) (OECD 471)
- In Vitro Mammalian Chromosomal Aberration Test (CHO cells) (OECD 473)
- In Vitro Mammalian Chromosomal Aberration Test (Human Peripheral Blood Lymphocytes-HPBL) (OECD 473)
- In Vitro Mammalian Cell Gene Mutation Test Using the Hprt and xprt genes (OECD 476)
- In Vitro Mammalian Cell Micronucleus Test (Human Peripheral Blood Lymphocytes-HPBL) (OECD 487)
- In Vitro Mammalian Cell Gene Mutation Test Using the Thymidine Kinase Gene (OECD 490)
- Mammalian Erythrocyte Micronucleus Test (OECD 474)
- Mammalian Bone Marrow Chromosomal Aberration Test (OECD 475)
In Vitro Studies
- EpiSkin-In Vitro Skin Corrosion (OECD 431)
- EpiSkin-In Vitro Skin Irritation (OECD 439)
- In Vitro Eye Irritation [Bovine Corneal Opacity and Permeability (BCOP) Test] (OECD 437)
- In Vitro Eye Irritation EpiOcular (OECD 492)
- In Vitro Skin Sensitization [Dermal Peptide Reactivity Assay (DPRA)] (OECD 442C)
- In Vitro Skin Sensitization- ARE-Nrf2 Luciferase Test Method [KeratinoSens] (OECD 442D)
- In Vitro Skin Sensitization [Human Cell Line (U937-U-SENS) Activation Test (h-CLAT)] (OECD 442E)
- In Vitro Skin Absorption: Franz Cell Diffusion Assay (OECD 428)
- In vitro Cytotoxicity in Balb/c 3T3 LD50 (OECD 129)
Acute Studies
- Acute Oral Toxicity Study in Rats (OECD 420/423/425)
- Acute Dermal Toxicity Study in Rats (OECD 402)
- Acute Inhalation Study in Rats (OECD 403)
- Acute Dermal Irritation/Corrosion Study in Rabbits (OECD 404)
- Acute Eye Irritation/Corrosion Study in Rabbits (OECD 405)
- Skin Sensitization Study in Guinea Pigs (OECD 406)
- Local Lymph Node Assay (LLNA) in CBA/Ca mice (OECD 429)
Repeated Dose
- Dose range finding (7 to 14 day) toxicology studies in Mice/Rats
- Dose range finding (7 to 14 day) toxicology studies in Beagle Dogs*
- 28-day repeat dose toxicity studies in Mice/Rats
- 28-day repeat dose toxicity studies in Beagle Dogs*
- 90-day repeat dose toxicity studies in Mice/Rats
- 90-day repeat dose toxicity studies in Beagle Dogs*
- 21/28-day repeat dose dermal toxicity studies in Rats/Rabbits
- 90-day repeat dose dermal toxicity studies in Rats/Rabbits
- 28-day Inhalation toxicity studies in Rats
- 90-day Inhalation toxicity studies in Rats
Developmental and Reproductive Toxicology Studies
- Prenatal Developmental Toxicity Study in Mice/rats/Rabbits (OECD 414)
- One Generation Reproductive Toxicity Study in Mice/Rats (OECD 415)
- Two Generation Reproductive Toxicity Study in Mice/Rats (OECD 416)
- Reproduction/Developmental Toxicity Screening Test in Rats (OECD 421)
- Combined Repeated Dose with Reproduction/Developmental Toxicity Screening Test in Rats (OECD 422)
- Extended One-Generation Reproduction Toxicity Study in Rats (OECD 443)
Endocrine Disruption Studies
- Uterotrophic Bioassay in Rats (OECD 440)
- Hershberger Bioassay in Rats (OECD 441)
Neurotoxicity Studies
- Delayed Neurotoxicity of Organophosphorus substances following acute exposure (OECD 418)
- Delayed Neurotoxicity of Organophosphorus substances 28-day repeated dose study (OECD 419)
- Neurotoxicity Study in Rats (OECD 424)
- Developmental Neurotoxicity Study in Rats (OECD 426)
Chronic / Carcinogenicity / Oncogenicity Studies
- Carcinogenicity study in Mice/Rats (OECD 451)
- Chronic Toxicity studies in Mice/Rats (OECD 452)
- Combined Chronic Toxicity/Carcinogenicity study in Mice/Rats (OECD 453)
Metabolism Studies-Using 14C labeled compounds
- Toxicokinetics/Mass balance study in rats (OECD 417)
- Skin absorption study in rats (OECD 427)
- Metabolism in Livestock -Goat, Chicken and Swine* (OECD 503)
- Residues in Livestock -Goat, Chicken and Swine* (OECD 505)
*: In-life phase performed at partner facility
Ecotoxicology (Ecotox) studies
- Acute toxicity test in fish*
- Acute toxicity test in daphnia*
- Acute toxicity test in alga*
- Acute toxicity test in earthworm*
- Acute toxicity test in honey bee (oral & contact)*
- Ready biodegradability study (carbon dioxide evolution test)*
- Acute Oral Toxicity Study in birds [Japanese Quails/Chicken/Pigeon] (OECD 223)
- Avian Dietary Toxicity Study in Japanese Quails (OECD 205)
- Reproductive Toxicity in Birds-Japanese Quails (OECD 206)
*: Performed in group company at the same campus
